Acylation of Heteroaromatic Amines: Facile and Efficient Synthesis of a New Class of 1,2,3-Triazolo[4,5-b]pyridine and Pyrazolo[4,3-b]pyridine Derivatives

Acylation of Heteroaromatic Amines: Facile and Efficient Synthesis of a New Class of 1,2,3-Triazolo[4,5-b]pyridine and Pyrazolo[4,3-b]pyridine Derivatives

1,2,3-Triazolo[4,5-b]pyridines and pyrazolo[4,3-b]pyridines can be readily prepared via cyanoacetylation reactions of 5-amino-1,2,3-triazoles 1a,b and 4-amino- pyrazole 2 followed by subsequent cyclization of the formed cyanoacetamides. Reactions of amines 1a,b with a mixture of p-nitrophenylacetic...

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Bibliographic Details
Main Authors: Mohamed H. Elnagdi, Saad Makhseed, Hamada Mohamed Ibrahim, Haider Behbehani
Format: Article
Language:English
Published: MDPI AG 2011-05-01
Series:Molecules
Subjects:
cyanoacetic acid
cyanoacetamides
triazolo[4,5-b]pyridine
pyrazolo[4,3-b]- pyridine
p-nitrophenylacetic acid
zeolite
Online Access:http://www.mdpi.com/1420-3049/16/5/3723/

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http://www.mdpi.com/1420-3049/16/5/3723/

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