A Convenient One-pot Synthesis of 2,3-Disubstituted Thieno[2,3-d]pyrimidin-4(3H)-ones from 2H-Thieno[2,3-d][1,3]oxazine-2,4(1H)-diones, Aromatic Aldehydes and Amines

A Convenient One-pot Synthesis of 2,3-Disubstituted Thieno[2,3-d]pyrimidin-4(3H)-ones from 2H-Thieno[2,3-d][1,3]oxazine-2,4(1H)-diones, Aromatic Aldehydes and Amines

Abstract An efficient, simple protocol has been established for convenient synthesis of novel 2,3-disubstituted thieno[2,3-d]pyrimidin-4(3H)-one derivatives in good to high yields through a one-pot, two-step and three-component reaction from 2H-thieno[2,3-d][1,3]oxazine-2,4(1H)-diones, aromatic alde...

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Main Authors: Feize Liu, Xueling Hou, Li Fei Nie, Khurshed Bozorov, Michael Decker, Guozheng Huang
Format: Article
Language:English
Published: Georg Thieme Verlag KG 2018-04-01
Series:SynOpen
Subjects:
thieno[2,3-d]pyrimidin-4(3h)-one
one-pot synthesis
intramolecular cyclization
pyrimidinone
quinazolinone
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0037-1610157
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spelling doaj-ca06f54ebf2b44c8a8063afcd82002b62020-11-25T03:14:45ZengGeorg Thieme Verlag KGSynOpen2509-93962018-04-0102020207021210.1055/s-0037-1610157A Convenient One-pot Synthesis of 2,3-Disubstituted Thieno[2,3-d]pyrimidin-4(3H)-ones from 2H-Thieno[2,3-d][1,3]oxazine-2,4(1H)-diones, Aromatic Aldehydes and AminesFeize Liu0Xueling Hou1Li Fei Nie2Khurshed Bozorov3Michael Decker4Guozheng Huang5Key Laboratory of Plant Resources and Chemistry of Arid Zone, Xinjiang Technical Institute of Physics and ChemistryKey Laboratory of Plant Resources and Chemistry of Arid Zone, Xinjiang Technical Institute of Physics and ChemistryKey Laboratory of Plant Resources and Chemistry of Arid Zone, Xinjiang Technical Institute of Physics and ChemistryKey Laboratory of Plant Resources and Chemistry of Arid Zone, Xinjiang Technical Institute of Physics and ChemistryPharmazeutische und Medizinische Chemie, Institut für Pharmazie und LebensmittelchemieKey Laboratory of Plant Resources and Chemistry of Arid Zone, Xinjiang Technical Institute of Physics and ChemistryAbstract An efficient, simple protocol has been established for convenient synthesis of novel 2,3-disubstituted thieno[2,3-d]pyrimidin-4(3H)-one derivatives in good to high yields through a one-pot, two-step and three-component reaction from 2H-thieno[2,3-d][1,3]oxazine-2,4(1H)-diones, aromatic aldehydes, and amines.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0037-1610157thieno[2,3-d]pyrimidin-4(3h)-oneone-pot synthesisintramolecular cyclizationpyrimidinonequinazolinone
collection DOAJ
language English
format Article
sources DOAJ
author Feize Liu
Xueling Hou
Li Fei Nie
Khurshed Bozorov
Michael Decker
Guozheng Huang
spellingShingle Feize Liu
Xueling Hou
Li Fei Nie
Khurshed Bozorov
Michael Decker
Guozheng Huang
A Convenient One-pot Synthesis of 2,3-Disubstituted Thieno[2,3-d]pyrimidin-4(3H)-ones from 2H-Thieno[2,3-d][1,3]oxazine-2,4(1H)-diones, Aromatic Aldehydes and Amines
SynOpen
thieno[2,3-d]pyrimidin-4(3h)-one
one-pot synthesis
intramolecular cyclization
pyrimidinone
quinazolinone
author_facet Feize Liu
Xueling Hou
Li Fei Nie
Khurshed Bozorov
Michael Decker
Guozheng Huang
author_sort Feize Liu
title A Convenient One-pot Synthesis of 2,3-Disubstituted Thieno[2,3-d]pyrimidin-4(3H)-ones from 2H-Thieno[2,3-d][1,3]oxazine-2,4(1H)-diones, Aromatic Aldehydes and Amines
title_short A Convenient One-pot Synthesis of 2,3-Disubstituted Thieno[2,3-d]pyrimidin-4(3H)-ones from 2H-Thieno[2,3-d][1,3]oxazine-2,4(1H)-diones, Aromatic Aldehydes and Amines
title_full A Convenient One-pot Synthesis of 2,3-Disubstituted Thieno[2,3-d]pyrimidin-4(3H)-ones from 2H-Thieno[2,3-d][1,3]oxazine-2,4(1H)-diones, Aromatic Aldehydes and Amines
title_fullStr A Convenient One-pot Synthesis of 2,3-Disubstituted Thieno[2,3-d]pyrimidin-4(3H)-ones from 2H-Thieno[2,3-d][1,3]oxazine-2,4(1H)-diones, Aromatic Aldehydes and Amines
title_full_unstemmed A Convenient One-pot Synthesis of 2,3-Disubstituted Thieno[2,3-d]pyrimidin-4(3H)-ones from 2H-Thieno[2,3-d][1,3]oxazine-2,4(1H)-diones, Aromatic Aldehydes and Amines
title_sort convenient one-pot synthesis of 2,3-disubstituted thieno[2,3-d]pyrimidin-4(3h)-ones from 2h-thieno[2,3-d][1,3]oxazine-2,4(1h)-diones, aromatic aldehydes and amines
publisher Georg Thieme Verlag KG
series SynOpen
issn 2509-9396
publishDate 2018-04-01
description Abstract An efficient, simple protocol has been established for convenient synthesis of novel 2,3-disubstituted thieno[2,3-d]pyrimidin-4(3H)-one derivatives in good to high yields through a one-pot, two-step and three-component reaction from 2H-thieno[2,3-d][1,3]oxazine-2,4(1H)-diones, aromatic aldehydes, and amines.
topic thieno[2,3-d]pyrimidin-4(3h)-one
one-pot synthesis
intramolecular cyclization
pyrimidinone
quinazolinone
url http://www.thieme-connect.de/DOI/DOI?10.1055/s-0037-1610157
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