Effect of Curcumin on Protein Damage Induced by Rotenone in Dopaminergic PC12 Cells

Effect of Curcumin on Protein Damage Induced by Rotenone in Dopaminergic PC12 Cells

Oxidative stress is considered to be a key factor of the pathogenesis of Parkinson’s disease, a multifactorial neurodegenerative disorder characterized by reduced dopaminergic neurons in the <i>substantia nigra pars compacta</i> and accumulated protein aggregates. Rotenone is a worldwide...

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Bibliographic Details
Main Authors: Sandra Buratta, Elisabetta Chiaradia, Alessia Tognoloni, Angela Gambelunghe, Consuelo Meschini, Luigi Palmieri, Giacomo Muzi, Lorena Urbanelli, Carla Emiliani, Brunella Tancini
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
rotenone
curcumin
PC12 cells
protein oxidation
oxidative stress
Parkinson’s disease
Online Access:https://www.mdpi.com/1422-0067/21/8/2761

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