Replication of Structured DNA and its implication in epigenetic stability

DNA replication is an extremely risky process that cells have to endure in order to correctly duplicate and segregate their genome. This task is particularly sensitive to DNA damage and multiple mechanisms have evolved to protect DNA replication as a block to the replication fork could lead to genom...

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Bibliographic Details
Main Authors: Valentina eCea, Lina eCipolla, Simone eSabbioneda
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-06-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00209/full