Control of Specific Growth Rate in Fed-Batch Bioprocesses: Novel Controller Design for Improved Noise Management
Accurate control of the specific growth rate (<i>µ</i>) of microorganisms is dependent on the ability to quantify the evolution of biomass reliably in real time. Biomass concentration can be monitored online using various tools and methods, but the obtained signal is often very noisy and...
Main Authors: | Yann Brignoli, Brian Freeland, David Cunningham, Michal Dabros |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-06-01
|
Series: | Processes |
Subjects: | |
Online Access: | https://www.mdpi.com/2227-9717/8/6/679 |
Similar Items
-
Preventing Overflow Metabolism in Crabtree-Positive Microorganisms through On-Line Monitoring and Control of Fed-Batch Fermentations
by: Loïc Habegger, et al.
Published: (2018-09-01) -
Application of Raman Spectroscopy and Univariate Modelling As a Process Analytical Technology for Cell Therapy Bioprocessing
by: Marc-Olivier Baradez, et al.
Published: (2018-03-01) -
A Soft Sensor for Bioprocess Control Based on Sequential Filtering of Metabolic Heat Signals
by: Dan Paulsson, et al.
Published: (2014-09-01) -
A Nuclear Magnetic Resonance (NMR) Platform for Real-Time Metabolic Monitoring of Bioprocesses
by: Ninad Mehendale, et al.
Published: (2020-10-01) -
Studies on the fed-batch propagation of brewer's yeast in high gravity wort
by: Zizhou, Njodzi
Published: (2014)