Modulation of Tight Junction Structure and Function by Kinases and Phosphatases Targeting Occludin

Tight junctions (TJs) typically represent the most apical contacts in epithelial and endothelial cell layers where they play an essential role in the separation of extracellular or luminal spaces from underlying tissues in the body. Depending on the protein composition, TJs define the barrier charac...

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Bibliographic Details
Main Authors: Max Johannes Dörfel, Otmar Huber
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Journal of Biomedicine and Biotechnology
Online Access:http://dx.doi.org/10.1155/2012/807356