Effects of Ethanolic Ferolagu angulata Extract on Pathogenic Gastrointestinal Bacteria and Probiotic Bacteria in Skimmed Milk Medium

• Main Authors: Reza Naghiha, Mokhtar Khajavi, Mohammad Reza Bahreini, Ali Naghi Keshtkaran
• Format: Article
• Language: English
• Published: Tehran University of Medical Sciences 2016-08-01
• Series: Journal of Medical Bacteriology
• Subjects: Probiotic bacteria; Chavill extract; Lactobacillus
• Online Access: http://jmb.tums.ac.ir/index.php/jmb/article/view/184
• ISSN: 2251-8649; 2322-2581

<div><table cellspacing="0" cellpadding="0" align="left"><tbody><tr><td align="left" valign="top"><p><strong><em>Background</em></strong><strong>:<em> </em></strong>   Due to excessive consumption of synthetic drugs, drug resistance rate of pathogenic bacteria is increasing and there is an ever-increasing need to find new safe compounds to tackle this problem. This study was conducted to investigate the consequences of chavill<em> </em>extract on the growth and viability of gastrointestinal pathogenic bacterium and probiotics bacteria. </p><p><strong><em>Methods</em></strong><strong>:<em> </em></strong>   The experiment contained three levels of the chavill<em> </em>extract concentrations (0, 1 and 3%) which were added to the milk free fat in accompany with three probiotic bacteria (<em>Lactobacillus acidophilus</em>, <em>Lactobacillus casei </em>and <em>lactobacillus plantaram) </em>and a pathogenic gastrointestinal bacterium (<em>Salmonella typhimurium</em>). Bacterial inoculums (1×10⁷CFU/ml) with different concentrations of chavill<em> </em>extract were added to skimmed milk medium and bacteria growth were enumerated. </p><p><strong><em>Results</em></strong><strong>:<em> </em></strong><em> </em>The concentration of 1% chavill<em> </em>extract significantly increased the total count of probiotic bacteria compared to the control group, while the number of pathogenic bacteria was decreased. At 3% chavill extract the growth of <em>Lactobacillus acidophilus </em>and <em>Lactobacillus plantaram </em>were increased. On the other hand, it prevented the growth of <em>Salmonella typhimurium</em> </p><p><strong><em>Conclusion</em></strong><strong>:<em> </em></strong>  Chavill<em> </em>extracts would play as an alternative to antibiotics in pharmacological studies to decreases harmful bacteria and increase probiotic bacteria.</p></td></tr></tbody></table></div>