Scoping Review on Use of Drugs Targeting Interleukin 1 Pathway in DIRA and DITRA

Scoping Review on Use of Drugs Targeting Interleukin 1 Pathway in DIRA and DITRA

Abstract Introduction Deficiencies in interleukin (IL)-1 receptor (IL-R) antagonist (DIRA) and IL-36R antagonist (DITRA) are rare genetic autoinflammatory diseases related to alterations in antagonists of the IL-1 pathway. IL-1 antagonists may represent therapeutic alternatives. Here, we aim to prov...

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Bibliographic Details
Main Authors: Francisco Gómez-García, Juan L. Sanz-Cabanillas, Isabel Viguera-Guerra, Beatriz Isla-Tejera, Antonio Vélez-García Nieto, Juan Ruano
Format: Article
Language:English
Published: Adis, Springer Healthcare 2018-11-01
Series:Dermatology and Therapy
Subjects:
Anakinra
Anti-IL-1 drugs
Canakinumab
Deficiency of interleukin(IL)-1 receptor(R) antagonist (DIRA)
Genetic autoinflammatory diseases
Deficiency of IL-36R antagonist (DITRA)
Online Access:http://link.springer.com/article/10.1007/s13555-018-0269-7

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http://link.springer.com/article/10.1007/s13555-018-0269-7

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