Olfactory Neuroblastoma Treated by Endoscopic Surgery Followed by Combined External Beam Radiation and Gamma Knife for Optic Nerve and Chiasm Sparing: A Case Report

We describe the multimodality treatment regimen of a 53-year-old man diagnosed with olfactory neuroblastoma (Kadish stage C) in the right nasal cavity extending into the ethmoid sinus and across the cribriform plate. Endoscopic surgery for tumor resection was followed by a combination of external be...

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Main Authors: Hansi Z. Jiang, Ameer L. Elaimy, Guy C. Jones, Alexander R. Mackay, Robert K. Fairbanks, Wayne T. Lamoreaux, John J. Demakas, Barton S. Cooke, Christopher M. Lee
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2011/765645
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spelling doaj-c9c6ea4bae3b4a319eb5e4bd797726022020-11-24T22:19:20ZengHindawi LimitedCase Reports in Medicine1687-96271687-96352011-01-01201110.1155/2011/765645765645Olfactory Neuroblastoma Treated by Endoscopic Surgery Followed by Combined External Beam Radiation and Gamma Knife for Optic Nerve and Chiasm Sparing: A Case ReportHansi Z. Jiang0Ameer L. Elaimy1Guy C. Jones2Alexander R. Mackay3Robert K. Fairbanks4Wayne T. Lamoreaux5John J. Demakas6Barton S. Cooke7Christopher M. Lee8Gamma Knife of Spokane, 910 W 5th Avenue, Suite 102, Spokane, WA 99204, USAGamma Knife of Spokane, 910 W 5th Avenue, Suite 102, Spokane, WA 99204, USAGamma Knife of Spokane, 910 W 5th Avenue, Suite 102, Spokane, WA 99204, USAGamma Knife of Spokane, 910 W 5th Avenue, Suite 102, Spokane, WA 99204, USAGamma Knife of Spokane, 910 W 5th Avenue, Suite 102, Spokane, WA 99204, USAGamma Knife of Spokane, 910 W 5th Avenue, Suite 102, Spokane, WA 99204, USAGamma Knife of Spokane, 910 W 5th Avenue, Suite 102, Spokane, WA 99204, USAGamma Knife of Spokane, 910 W 5th Avenue, Suite 102, Spokane, WA 99204, USAGamma Knife of Spokane, 910 W 5th Avenue, Suite 102, Spokane, WA 99204, USAWe describe the multimodality treatment regimen of a 53-year-old man diagnosed with olfactory neuroblastoma (Kadish stage C) in the right nasal cavity extending into the ethmoid sinus and across the cribriform plate. Endoscopic surgery for tumor resection was followed by a combination of external beam radiotherapy and stereotactic radiosurgery boost with concurrent chemotherapy. The novel combination of dual radiation therapies allowed for the preservation of the nearby optic structures while providing an adequate dosage to a sufficient volume of the afflicted tissue.http://dx.doi.org/10.1155/2011/765645
collection DOAJ
language English
format Article
sources DOAJ
author Hansi Z. Jiang
Ameer L. Elaimy
Guy C. Jones
Alexander R. Mackay
Robert K. Fairbanks
Wayne T. Lamoreaux
John J. Demakas
Barton S. Cooke
Christopher M. Lee
spellingShingle Hansi Z. Jiang
Ameer L. Elaimy
Guy C. Jones
Alexander R. Mackay
Robert K. Fairbanks
Wayne T. Lamoreaux
John J. Demakas
Barton S. Cooke
Christopher M. Lee
Olfactory Neuroblastoma Treated by Endoscopic Surgery Followed by Combined External Beam Radiation and Gamma Knife for Optic Nerve and Chiasm Sparing: A Case Report
Case Reports in Medicine
author_facet Hansi Z. Jiang
Ameer L. Elaimy
Guy C. Jones
Alexander R. Mackay
Robert K. Fairbanks
Wayne T. Lamoreaux
John J. Demakas
Barton S. Cooke
Christopher M. Lee
author_sort Hansi Z. Jiang
title Olfactory Neuroblastoma Treated by Endoscopic Surgery Followed by Combined External Beam Radiation and Gamma Knife for Optic Nerve and Chiasm Sparing: A Case Report
title_short Olfactory Neuroblastoma Treated by Endoscopic Surgery Followed by Combined External Beam Radiation and Gamma Knife for Optic Nerve and Chiasm Sparing: A Case Report
title_full Olfactory Neuroblastoma Treated by Endoscopic Surgery Followed by Combined External Beam Radiation and Gamma Knife for Optic Nerve and Chiasm Sparing: A Case Report
title_fullStr Olfactory Neuroblastoma Treated by Endoscopic Surgery Followed by Combined External Beam Radiation and Gamma Knife for Optic Nerve and Chiasm Sparing: A Case Report
title_full_unstemmed Olfactory Neuroblastoma Treated by Endoscopic Surgery Followed by Combined External Beam Radiation and Gamma Knife for Optic Nerve and Chiasm Sparing: A Case Report
title_sort olfactory neuroblastoma treated by endoscopic surgery followed by combined external beam radiation and gamma knife for optic nerve and chiasm sparing: a case report
publisher Hindawi Limited
series Case Reports in Medicine
issn 1687-9627
1687-9635
publishDate 2011-01-01
description We describe the multimodality treatment regimen of a 53-year-old man diagnosed with olfactory neuroblastoma (Kadish stage C) in the right nasal cavity extending into the ethmoid sinus and across the cribriform plate. Endoscopic surgery for tumor resection was followed by a combination of external beam radiotherapy and stereotactic radiosurgery boost with concurrent chemotherapy. The novel combination of dual radiation therapies allowed for the preservation of the nearby optic structures while providing an adequate dosage to a sufficient volume of the afflicted tissue.
url http://dx.doi.org/10.1155/2011/765645
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