Hepatocellular-Targeted mRNA Delivery Using Functionalized Selenium Nanoparticles In Vitro

Hepatocellular-Targeted mRNA Delivery Using Functionalized Selenium Nanoparticles In Vitro

Selenium’s (Se) chemopreventative and therapeutic properties have attracted attention in nanomedicine. Se nanoparticles (SeNPs) retain these properties of Se while possessing lower toxicity and higher bioavailability, potentiating their use in gene delivery. This study aimed to formulate SeNPs for e...

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Bibliographic Details
Main Authors: Dhireshan Singh, Moganavelli Singh
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Pharmaceutics
Subjects:
Selenium nanoparticles
F<i>Luc</i>-mRNA
lactobionic acid
chitosan
targeting
gene expression
Online Access:https://www.mdpi.com/1999-4923/13/3/298

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