Cardiovascular disease prevalence in type 2 diabetes – an analysis of a large German statutory health insurance database
Abstract Background The aim of this study was to determine the prevalence of cardiovascular disease in persons with type 2 diabetes mellitus (T2D) in Germany. Methods A claims database with an age- and sex-stratified sample of nearly 4 million individuals insured within the German statutory health s...
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doaj-c9bbbd2043f64987a843750c879708f82021-02-14T12:03:58ZengBMCBMC Public Health1471-24582021-02-012111910.1186/s12889-021-10381-zCardiovascular disease prevalence in type 2 diabetes – an analysis of a large German statutory health insurance databaseMaximilian Gabler0Silke Geier1Lukas Mayerhoff2Wolfgang Rathmann3Boehringer IngelheimBoehringer IngelheimFormer employee of Elsevier Health AnalyticsInstitute for Biometrics and Epidemiology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine UniversityAbstract Background The aim of this study was to determine the prevalence of cardiovascular disease in persons with type 2 diabetes mellitus (T2D) in Germany. Methods A claims database with an age- and sex-stratified sample of nearly 4 million individuals insured within the German statutory health system was used. All patients aged ≥18 years with T2D documented between 1 January 2015 and 31 December 2015 and complete retrospective documentation of ≥5 years (continuous enrollment in the German statutory health system) before 2015 were selected based on a validated algorithm. Cardiovascular disease (CVD) events were identified based on ICD-10 and OPS codes according to a previous clinical study (EMPA-REG OUTCOME trial). Results The prevalence of T2D in Germany in 2015 was 9.9% (n = 324,708). Using a narrow definition of CVD, the 6-year observation period prevalence of CVD was estimated as 46.7% [95% CI: 46.52%;46.86%]. Applying a wider CVD definition, the proportion of T2D patients who showed a history of CVD was 57.1% [95% CI: 56.9%;57.24%]. The prevalence of CVD in patients with T2D ranged from 36.3 to 57.1%, depending on the observation period and definition of CVD. Conclusions The results underline the need for a population-based registration of cardiovascular complications in T2D.https://doi.org/10.1186/s12889-021-10381-zSecondary data analysisEpidemiological studyPrevalence figuresType 2 diabetes mellitusCardiovascular disease |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Maximilian Gabler Silke Geier Lukas Mayerhoff Wolfgang Rathmann |
spellingShingle |
Maximilian Gabler Silke Geier Lukas Mayerhoff Wolfgang Rathmann Cardiovascular disease prevalence in type 2 diabetes – an analysis of a large German statutory health insurance database BMC Public Health Secondary data analysis Epidemiological study Prevalence figures Type 2 diabetes mellitus Cardiovascular disease |
author_facet |
Maximilian Gabler Silke Geier Lukas Mayerhoff Wolfgang Rathmann |
author_sort |
Maximilian Gabler |
title |
Cardiovascular disease prevalence in type 2 diabetes – an analysis of a large German statutory health insurance database |
title_short |
Cardiovascular disease prevalence in type 2 diabetes – an analysis of a large German statutory health insurance database |
title_full |
Cardiovascular disease prevalence in type 2 diabetes – an analysis of a large German statutory health insurance database |
title_fullStr |
Cardiovascular disease prevalence in type 2 diabetes – an analysis of a large German statutory health insurance database |
title_full_unstemmed |
Cardiovascular disease prevalence in type 2 diabetes – an analysis of a large German statutory health insurance database |
title_sort |
cardiovascular disease prevalence in type 2 diabetes – an analysis of a large german statutory health insurance database |
publisher |
BMC |
series |
BMC Public Health |
issn |
1471-2458 |
publishDate |
2021-02-01 |
description |
Abstract Background The aim of this study was to determine the prevalence of cardiovascular disease in persons with type 2 diabetes mellitus (T2D) in Germany. Methods A claims database with an age- and sex-stratified sample of nearly 4 million individuals insured within the German statutory health system was used. All patients aged ≥18 years with T2D documented between 1 January 2015 and 31 December 2015 and complete retrospective documentation of ≥5 years (continuous enrollment in the German statutory health system) before 2015 were selected based on a validated algorithm. Cardiovascular disease (CVD) events were identified based on ICD-10 and OPS codes according to a previous clinical study (EMPA-REG OUTCOME trial). Results The prevalence of T2D in Germany in 2015 was 9.9% (n = 324,708). Using a narrow definition of CVD, the 6-year observation period prevalence of CVD was estimated as 46.7% [95% CI: 46.52%;46.86%]. Applying a wider CVD definition, the proportion of T2D patients who showed a history of CVD was 57.1% [95% CI: 56.9%;57.24%]. The prevalence of CVD in patients with T2D ranged from 36.3 to 57.1%, depending on the observation period and definition of CVD. Conclusions The results underline the need for a population-based registration of cardiovascular complications in T2D. |
topic |
Secondary data analysis Epidemiological study Prevalence figures Type 2 diabetes mellitus Cardiovascular disease |
url |
https://doi.org/10.1186/s12889-021-10381-z |
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