Assessing the benefits of using mate-pairs to resolve repeats in de novo short-read prokaryotic assemblies

<p>Abstract</p> <p>Background</p> <p>Next-generation sequencing technologies allow genomes to be sequenced more quickly and less expensively than ever before. However, as sequencing technology has improved, the difficulty of <it>de novo </it>genome assembly...

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Bibliographic Details
Main Authors: Pop Mihai, Kingsford Carl, Wetzel Joshua
Format: Article
Language:English
Published: BMC 2011-04-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/12/95