Non-canonical NF-κB signalling initiated by BAFF influences B cell biology at multiple junctures

It has been more than a decade since it was recognised that the nuclear factor of kappa light polypeptide gene enhancer in B cells (NF-κB) transcription factor family was activated by two distinct pathways: the canonical pathway involving NF-κB1 and the non-canonical pathway involving NF-κB2. During...

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Bibliographic Details
Main Authors: Sandra eGardam, Robert eBrink
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-01-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00509/full