Milnacipran inhibits glutamatergic <it>N</it>-Methyl-D-Aspartate receptor activity in Spinal Dorsal Horn Neurons

Milnacipran inhibits glutamatergic <it>N</it>-Methyl-D-Aspartate receptor activity in Spinal Dorsal Horn Neurons

<p>Abstract</p> <p>Background</p> <p>Antidepressants, which are widely used for treatment of chronic pain, are thought to have antinociceptive effects by blockade of serotonin and noradrenaline reuptake. However, these drugs also interact with various receptors such as...

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Bibliographic Details
Main Authors: Kohno Tatsuro, Kimura Masafumi, Sasaki Mika, Obata Hideaki, Amaya Fumimasa, Saito Shigeru
Format: Article
Language:English
Published: SAGE Publishing 2012-06-01
Series:Molecular Pain
Subjects:
Antidepressants
<it>N</it>-methyl-D-aspartate (NMDA) Receptor
Spinal Analgesia
Online Access:http://www.molecularpain.com/content/8/1/45

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