TREM-1 links dyslipidemia to inflammation and lipid deposition in atherosclerosis
TREM-1 is a receptor that amplifies acute pro-inflammatory responses in infection. Here the authors show that TREM-1 plays an important role in atherosclerosis, a chronic and non-infectious disease, by critically skewing myelopoiesis towards preferential monocyte differentiation and by contributing...
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Bibliographic Details
Main Authors: |
Daniel Zysset,
Benjamin Weber,
Silvia Rihs,
Jennifer Brasseit,
Stefan Freigang,
Carsten Riether,
Yara Banz,
Adelheid Cerwenka,
Cedric Simillion,
Pedro Marques-Vidal,
Adrian F. Ochsenbein,
Leslie Saurer,
Christoph Mueller |
Format: | Article
|
Language: | English |
Published: |
Nature Publishing Group
2016-10-01
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Series: | Nature Communications
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Online Access: | https://doi.org/10.1038/ncomms13151
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