Four Simple Biomimetic Mineralization Methods to Improve the Thermostability and Immunogenicity of Virus-like Particles as a Vaccine against Foot-and-Mouth Disease

Four Simple Biomimetic Mineralization Methods to Improve the Thermostability and Immunogenicity of Virus-like Particles as a Vaccine against Foot-and-Mouth Disease

The need for a cold chain system during storage and transport substantially increases the cost of vaccines. Virus-like particles (VLPs) are among the best countermeasures against foot and mouth disease virus (FMDV). However, VLPs are composed of pure proteins, and thus, are susceptible to heat. To a...

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Bibliographic Details
Main Authors: Mengnan Guo, Jiajun Li, Zhidong Teng, Mei Ren, Hu Dong, Yun Zhang, Jiaxi Ru, Ping Du, Shiqi Sun, Huichen Guo
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Vaccines
Subjects:
foot-and-mouth disease
virus-like particles
biomineralization
thermal stability
biomimetic
Online Access:https://www.mdpi.com/2076-393X/9/8/891

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