Sustained analgesic effect of clonidine co-polymer depot in a porcine incisional pain model

Sustained analgesic effect of clonidine co-polymer depot in a porcine incisional pain model

Jared T Wilsey, Julie H Block Medtronic Spine Division, Memphis, TN, USA Background: Previous research suggests that the α2 adrenergic agonist clonidine, a centrally acting analgesic and antihypertensive, may also have direct effects on peripheral pain generators. However, aqueous...

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Bibliographic Details
Main Authors: Wilsey JT, Block JH
Format: Article
Language:English
Published: Dove Medical Press 2018-04-01
Series:Journal of Pain Research
Subjects:
amide anesthetic
bio-erodible polymer
peripherally acting analgesic
imidazoline
porcine model
post-operative pain
regional anesthesia
sustained release
Online Access:https://www.dovepress.com/sustained-analgesic-effect-of-clonidine-co-polymer-depot-in-a-porcine--peer-reviewed-article-JPR

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https://www.dovepress.com/sustained-analgesic-effect-of-clonidine-co-polymer-depot-in-a-porcine--peer-reviewed-article-JPR

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