A novel in vitro system for intracellular delivery of nonviral DNA

A novel in vitro system for intracellular delivery of nonviral DNA

Articular chondrocytes are the main cell population in cartilage, and damage to them is a key step in osteoarthritis. There are chondrocyte-based strategies to treat osteoarthritis, among which includes nonviral gene therapy. However, so far there is no ideal way to achieve this because chondrocyte...

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Bibliographic Details
Main Authors: Haijun Tong, Hongqiang Liu, Yiyun Wang, Fei Yang, Qin Shi, Julio C. Fernandes, Kerong Dai, Xiaoling Zhang
Format: Article
Language:English
Published: Elsevier 2014-07-01
Series:Journal of Orthopaedic Translation
Subjects:
intracellular tracking
Nonviral DNA delivery system
Polyplex
Rate-limit zone
Real-time imaging
Online Access:http://www.sciencedirect.com/science/article/pii/S2214031X14000485

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http://www.sciencedirect.com/science/article/pii/S2214031X14000485

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