| Summary: | N6-methyladenosine (m<sup>6</sup>A) has been identified in various biological processes and plays important regulatory functions in diverse cells. However, there is still no visualization database for exploring global m<sup>6</sup>A patterns across cell lines. Here we collected all available MeRIP-Seq and m<sup>6</sup>A-CLIP-Seq datasets from public databases and identified 340,950 and 179,201 m<sup>6</sup>A peaks dependent on 23 human and eight mouse cell lines respectively. Those m<sup>6</sup>A peaks were further classified into mRNA and lncRNA groups. To better understand the potential function of m<sup>6</sup>A, we then mapped m<sup>6</sup>A peaks in different subcellular components and gene regions. Among those human m<sup>6</sup>A modification, 190,050 and 150,900 peaks were identified in cancer and non-cancer cells, respectively. Finally, all results were integrated and imported into a visualized cell-dependent m<sup>6</sup>A database CVm6A. We believe the specificity of CVm6A could significantly contribute to the research for the function and regulation of cell-dependent m<sup>6</sup>A modification in disease and development.
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