Outcome of Laparoscopic Live Donor Nephrectomy and Impact of Double Renal Arteries: Results From Two Transplant Centres

Live donor kidney transplantation is consistently superior to deceased donor kidney transplantation. Laparoscopic donor nephrectomy (LDN) is increasingly accepted as a safe and preferred surgical option. To evaluate the outcome of LDN and the impact of multiple arteries, a retrospective review was c...

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Main Authors: Tricia Kuo, Sidney Kam-Hung Yip, Chi Fai Ng, Lay Guat Ng, Christopher Wai-Sam Cheng
Format: Article
Language:English
Published: Elsevier 2010-04-01
Series:Asian Journal of Surgery
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1015958410600127
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spelling doaj-c967fe6523554fd2966ca499ab916b162020-11-24T21:28:25ZengElsevierAsian Journal of Surgery1015-95842010-04-01332707510.1016/S1015-9584(10)60012-7Outcome of Laparoscopic Live Donor Nephrectomy and Impact of Double Renal Arteries: Results From Two Transplant CentresTricia Kuo0Sidney Kam-Hung Yip1Chi Fai Ng2Lay Guat Ng3Christopher Wai-Sam Cheng4Singapore General Hospital, SingaporeChinese University of Hong Kong, Hong Kong SARChinese University of Hong Kong, Hong Kong SARSingapore General Hospital, SingaporeSingapore General Hospital, SingaporeLive donor kidney transplantation is consistently superior to deceased donor kidney transplantation. Laparoscopic donor nephrectomy (LDN) is increasingly accepted as a safe and preferred surgical option. To evaluate the outcome of LDN and the impact of multiple arteries, a retrospective review was conducted on patients in two transplant centres. Methods: Fifty patients including eight with double vessels were studied. Standard left transperitoneal LDN was performed. Grafts including those with double vessels were prepared using the bench technique. Postoperative outcomes (up to 1 year) for donors and recipients were studied. The outcomes of recipients of a single or double vessel graft were compared. Results: All donors had an eventful recovery. No difference was found between the single and multiple vessels groups for operating time (168.21 ± 5.712 minutes vs. 197.50 ± 15.755 minutes) or hospital stay (3.21±0.165 days vs. 4.13±0.789 days). The recipient outcomes including hospital stay (10.17±0.596 days vs. 12.13 ± 1.797 days) and creatinine levels at day 7 (106.53 ± 5.583 μmol/L vs. 107.13 ± 11.857 μmol/L) and 1 year (120.21 ± 6.562 μmol/L vs. 124.75 ± 11.857 μmol/L) were similar. No ureteric stricture or graft loss was noted at 1-year follow-up. Recipient complications included lymphocoele (n = 2), haematoma (n = 3 with 2 requiring exploration), sepsis (n = 1), renal artery stenosis (n = 2 with 1 stented), repeated anastomosis (n = 1), and incisional hernia (n = 1). No differences were noted between the two groups. Conclusion: Our results showed that overall donor morbidity rate was low, as reflected by the short hospital stay. Also, the overall parameters of the recipients were good. In particular, no ureteric stricture was noted, and graft survival was 100% at 1 year. The outcomes of the reconstructed group, despite the technical challenge, were similar to those of the single-vessel group.http://www.sciencedirect.com/science/article/pii/S1015958410600127laparoscopic donor nephrectomykidney transplantation
collection DOAJ
language English
format Article
sources DOAJ
author Tricia Kuo
Sidney Kam-Hung Yip
Chi Fai Ng
Lay Guat Ng
Christopher Wai-Sam Cheng
spellingShingle Tricia Kuo
Sidney Kam-Hung Yip
Chi Fai Ng
Lay Guat Ng
Christopher Wai-Sam Cheng
Outcome of Laparoscopic Live Donor Nephrectomy and Impact of Double Renal Arteries: Results From Two Transplant Centres
Asian Journal of Surgery
laparoscopic donor nephrectomy
kidney transplantation
author_facet Tricia Kuo
Sidney Kam-Hung Yip
Chi Fai Ng
Lay Guat Ng
Christopher Wai-Sam Cheng
author_sort Tricia Kuo
title Outcome of Laparoscopic Live Donor Nephrectomy and Impact of Double Renal Arteries: Results From Two Transplant Centres
title_short Outcome of Laparoscopic Live Donor Nephrectomy and Impact of Double Renal Arteries: Results From Two Transplant Centres
title_full Outcome of Laparoscopic Live Donor Nephrectomy and Impact of Double Renal Arteries: Results From Two Transplant Centres
title_fullStr Outcome of Laparoscopic Live Donor Nephrectomy and Impact of Double Renal Arteries: Results From Two Transplant Centres
title_full_unstemmed Outcome of Laparoscopic Live Donor Nephrectomy and Impact of Double Renal Arteries: Results From Two Transplant Centres
title_sort outcome of laparoscopic live donor nephrectomy and impact of double renal arteries: results from two transplant centres
publisher Elsevier
series Asian Journal of Surgery
issn 1015-9584
publishDate 2010-04-01
description Live donor kidney transplantation is consistently superior to deceased donor kidney transplantation. Laparoscopic donor nephrectomy (LDN) is increasingly accepted as a safe and preferred surgical option. To evaluate the outcome of LDN and the impact of multiple arteries, a retrospective review was conducted on patients in two transplant centres. Methods: Fifty patients including eight with double vessels were studied. Standard left transperitoneal LDN was performed. Grafts including those with double vessels were prepared using the bench technique. Postoperative outcomes (up to 1 year) for donors and recipients were studied. The outcomes of recipients of a single or double vessel graft were compared. Results: All donors had an eventful recovery. No difference was found between the single and multiple vessels groups for operating time (168.21 ± 5.712 minutes vs. 197.50 ± 15.755 minutes) or hospital stay (3.21±0.165 days vs. 4.13±0.789 days). The recipient outcomes including hospital stay (10.17±0.596 days vs. 12.13 ± 1.797 days) and creatinine levels at day 7 (106.53 ± 5.583 μmol/L vs. 107.13 ± 11.857 μmol/L) and 1 year (120.21 ± 6.562 μmol/L vs. 124.75 ± 11.857 μmol/L) were similar. No ureteric stricture or graft loss was noted at 1-year follow-up. Recipient complications included lymphocoele (n = 2), haematoma (n = 3 with 2 requiring exploration), sepsis (n = 1), renal artery stenosis (n = 2 with 1 stented), repeated anastomosis (n = 1), and incisional hernia (n = 1). No differences were noted between the two groups. Conclusion: Our results showed that overall donor morbidity rate was low, as reflected by the short hospital stay. Also, the overall parameters of the recipients were good. In particular, no ureteric stricture was noted, and graft survival was 100% at 1 year. The outcomes of the reconstructed group, despite the technical challenge, were similar to those of the single-vessel group.
topic laparoscopic donor nephrectomy
kidney transplantation
url http://www.sciencedirect.com/science/article/pii/S1015958410600127
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