How does binding of agonist ligands control intrinsic molecular dynamics in human NMDA receptors?

How does binding of agonist ligands control intrinsic molecular dynamics in human NMDA receptors?

NMDA-type glutamate receptors (NMDAR) are ligand-gated ion channels that contribute to excitatory neurotransmission in the central nervous system. NMDAR dysfunction has been found to be involved in various neurological disorders. Recent crystallographic and EM studies have shown the static structure...

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Bibliographic Details
Main Authors:	Zoltan Palmai, Kimberley Houenoussi, Sylvia Cohen-Kaminsky, Luba Tchertanov
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2018-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC6075769?pdf=render

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