Intravenous palonosetron increases the incidence of QTc prolongation during sevoflurane general anesthesia for laparotomy

Intravenous palonosetron increases the incidence of QTc prolongation during sevoflurane general anesthesia for laparotomy

BackgroundPalonosetron is a recently introduced 5-hydroxytryptamine-3 (5-HT3) receptor antagonist useful for postoperative nausea and vomiting prophylaxis. However, 5-HT3 receptor antagonists increase the corrected QT (QTc) interval in patients who undergo general anesthesia. This retrospective stud...

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Bibliographic Details
Main Authors: Jeong Jin Min, Yongjae Yoo, Tae Kyong Kim, Jung-Man Lee
Format: Article
Language:English
Published: Korean Society of Anesthesiologists 2013-11-01
Series:Korean Journal of Anesthesiology
Subjects:
cardiac arrhythmia
electrocardiography
general anesthesia
palonosetron
patient safety
sevoflurane
Online Access:http://ekja.org/upload/pdf/kjae-65-397.pdf

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