Development of a competitive enzyme-linked immunosorbent assay for therapeutic drug monitoring of afatinib

Development of a competitive enzyme-linked immunosorbent assay for therapeutic drug monitoring of afatinib

Afatinib is an oral tyrosine kinase inhibitor (TKI) approved for treating advanced non-small cell lung cancer. It is necessary to develop a simple quantification method for TKIs in order to facilitate therapeutic drug monitoring (TDM) in clinical settings. This study sought to develop a simple and s...

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Bibliographic Details
Main Authors: Rintaro Sogawa, Tetsuya Saita, Yuta Yamamoto, Sakiko Kimura, Yutaka Narisawa, Shinya Kimura, Masashi Shin
Format: Article
Language:English
Published: Elsevier 2019-02-01
Series:Journal of Pharmaceutical Analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177918303083

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http://www.sciencedirect.com/science/article/pii/S2095177918303083

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