Mechanisms Underlying Therapeutic Effects Of Traditional Chinese Medicine On Gastric Cancer

• Main Authors: Yang L, Zhao L, Zeng T, Chen H, Shao J, Yang S, Tao Z, Yang J, Chen T, Lin X, Chen X, Tang M
• Format: Article
• Language: English
• Published: Dove Medical Press 2019-09-01
• Series: Cancer Management and Research
• Subjects: Chinese medicine; Metastasis; Gastric cancer; Cell cycle; Angiogenesis
• Online Access: https://www.dovepress.com/mechanisms-underlying-therapeutic-effects-of-traditional-chinese-medic-peer-reviewed-article-CMAR

Linjun Yang,1,* Liqian Zhao,1,* Tianni Zeng,1 Hong Chen,1 Jingjing Shao,1 Song Yang,1 Zheying Tao,1 Jingqin Yang,1 Tongke Chen,1 Xiaokun Lin,2 Xiwen Chen,1 Mosheng Tang3 1Department of Laboratory Animal Centre, Laboratory Animal Centre, Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China; 2Department of Pediatric Surgery, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China; 3Department of Radiotherapy and Chemotherapy, Lishui City People’s Hospital, The Sixth Affiliated Hospital of Wenzhou Medical University, Lishui, Zhejiang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Mosheng TangDepartment of Radiotherapy and Chemotherapy, Lishui City People’s Hospital, The Sixth Affiliated Hospital of Wenzhou Medical University, Lishui, Zhejiang, People’s Republic of ChinaTel [phone]Email [e-mail] ChenLaboratory Animal Centre, Wenzhou Medical University, Lucheng district, Wenzhou, Zhejiang, People’s Republic of ChinaTel [phone]Email [e-mail]: Gastric cancer (GC) is one of the most common malignant tumors in the world. It is the fourth most common cancer and has the second highest mortality rate globally. Metastasis is an important feature of gastric cancer and is the most common cause of death. Exploring the mechanism underlying the metastasis of gastric cancer and searching for new drug targets has become the focus of several studies. Traditional Chinese medicine may show promise for treatment of gastric cancer. In this review, we report the recent progress in research on the anti-metastasis activity of Chinese medicine, to facilitate clinical development of treatments for gastric cancer.Keywords: Chinese medicine, metastasis, gastric cancer, cell cycle, angiogenesis