Protective efficacy of baculovirus dual expression system vaccine expressing Plasmodium falciparum circumsporozoite protein.

Protective efficacy of baculovirus dual expression system vaccine expressing Plasmodium falciparum circumsporozoite protein.

We have previously developed a new malaria vaccine delivery system based on the baculovirus dual expression system (BDES). In this system, expression of malaria antigens is driven by a dual promoter consisting of the baculovirus-derived polyhedrin and mammal-derived cytomegalovirus promoters. To tes...

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Main Authors: Mitsuhiro Iyori, Hiroki Nakaya, Katsuya Inagaki, Sathit Pichyangkul, Daisuke S Yamamoto, Masanori Kawasaki, Kyungtak Kwak, Masami Mizukoshi, Yoshihiro Goto, Hiroyuki Matsuoka, Makoto Matsumoto, Shigeto Yoshida
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3741388?pdf=render

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