Cyclosporin A differentially inhibits multiple steps in VEGF induced angiogenesis in human microvascular endothelial cells through altered intracellular signaling

Cyclosporin A differentially inhibits multiple steps in VEGF induced angiogenesis in human microvascular endothelial cells through altered intracellular signaling

<p>Abstract</p> <p>The immunosuppressive agent cyclosporin A (CsA), a calcineurin inhibitor which blocks T cell activation has provided the pharmacologic foundation for organ transplantation. CsA exerts additional effects on non-immune cell populations and may adversely effect micr...

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Bibliographic Details
Main Authors: Li Mona S, Fisher Pamela J, Johnson Nathan A, Ogawa Hitoshi, Heidemann Jan, Rafiee Parvaneh, Otterson Mary F, Johnson Christopher P, Binion David G
Format: Article
Language:English
Published: BMC 2004-06-01
Series:Cell Communication and Signaling
Online Access:http://www.biosignaling.com/content/2/1/3

Internet

http://www.biosignaling.com/content/2/1/3

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