The evolutionary differentiation of two histone H2A.Z variants in chordates (H2A.Z-1 and H2A.Z-2) is mediated by a stepwise mutation process that affects three amino acid residues

The evolutionary differentiation of two histone H2A.Z variants in chordates (H2A.Z-1 and H2A.Z-2) is mediated by a stepwise mutation process that affects three amino acid residues

<p>Abstract</p> <p>Background</p> <p>The histone H2A family encompasses the greatest number of core histone variants of which the replacement variant H2A.Z is currently one of the most heavily studied. No clear mechanism for the functional variability that H2A.Z imparts...

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Bibliographic Details
Main Authors: Ausió Juan, Ishibashi Toyotaka, Dryhurst Deanna, González-Romero Rodrigo, Eirín-López José M
Format: Article
Language:English
Published: BMC 2009-02-01
Series:BMC Evolutionary Biology
Online Access:http://www.biomedcentral.com/1471-2148/9/31

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