Detection and Correlation of Single and Concomitant <i>TP53</i>, <i>PTEN,</i> and <i>CDKN2A</i> Alterations in Gliomas

Detection and Correlation of Single and Concomitant <i>TP53</i>, <i>PTEN,</i> and <i>CDKN2A</i> Alterations in Gliomas

Gliomas are the most frequent primary tumors of central nervous system and represent a heterogeneous group of tumors that originates from the glial cells. <i>TP53</i>, <i>PTEN</i>, and <i>CDKN2A</i> are important tumor suppressor genes that encode proteins involve...

Full description

Bibliographic Details
Main Authors:	Igor Andrade Pessôa, Carolina Koury Amorim, Wallax Augusto Silva Ferreira, Fernanda Sagica, José Reginaldo Brito, Moneeb Othman, Britta Meyer, Thomas Liehr, Edivaldo Herculano C. de Oliveira
Format:	Article
Language:	English
Published:	MDPI AG 2019-05-01
Series:	International Journal of Molecular Sciences
Subjects:	glioma <i>TP53</i> <i>PTEN</i> <i>CDKN2A</i> co-alterations single-strand conformational polymorphism array-comparative genomic hybridization and fluorescence in situ hybridization
Online Access:	https://www.mdpi.com/1422-0067/20/11/2658

Similar Items

High Positive Correlations between <i>ANRIL</i> and <i>p16</i>-<i>CDKN2A</i>/<i>p15</i>-<i>CDKN2B</i>/<i>p14</i>-<i>ARF</i> Gene Cluster Overexpression in Multi-Tumor Types Suggest Deregulated Activation of an <i>ANRIL–ARF</i> Bidirectional Promoter
by: Kinan Drak Alsibai, et al.
Published: (2019-08-01)

Deletion of <i>ptn1</i>, a <i>PTEN</i>/<i>TEP1</i> Orthologue, in <i>Ustilago maydis</i> Reduces Pathogenicity and Teliospore Development
by: Lalu M. K. Vijayakrishnapillai, et al.
Published: (2018-12-01)

The prognostic role of aberrant copy number of <i>DDB1, PRPF19, CDKN1B, с-Myc</i> genes in ovarian cancer patients
by: E. V. Verenikina, et al.
Published: (2021-07-01)

ERBB2 Regulates MED24 during Cancer Progression in Mice with <i>Pten</i> and <i>Smad4</i> Deletion in the Pulmonary Epithelium
by: Jian Liu, et al.
Published: (2019-06-01)

Molecular Profiling of 22 Primary Atypical Meningiomas Shows the Prognostic Significance of 18q Heterozygous Loss and <i>CDKN2A/B</i> Homozygous Deletion on Recurrence-Free Survival
by: Valeria Barresi, et al.
Published: (2021-02-01)

<i>PTEN</i> Hamartoma Tumor Syndrome: A Clinical Overview
by: Robert Pilarski
Published: (2019-06-01)

Molecular Cloning and Functional Characterization of the <i>DELLA</i> Gene Family in <i>Liriodendron </i>Hybrids
by: Yang Liu, et al.
Published: (2020-12-01)

Environmental Enrichment Rescues Social Behavioral Deficits and Synaptic Abnormalities in <i>Pten</i> Haploinsufficient Mice
by: Amy E. Clipperton-Allen, et al.
Published: (2021-08-01)

RNA <i>In Situ</i> Hybridization for Detecting Gene Expression Patterns in the Abdomens and Wings of <i>Drosophila</i> Species
by: Mujeeb Shittu, et al.
Published: (2021-03-01)

Fetal Megalencephaly with Cortical Dysplasia at 18 Gestational Weeks Related to Paternal UPD Mosaicism with <i>PTEN</i> Mutation
by: Ritsuko Kimata Pooh, et al.
Published: (2021-03-01)

Comparative Distribution of Repetitive Sequences in the Karyotypes of <i>Xenopus tropicalis</i> and <i>Xenopus laevis</i> (Anura, Pipidae)
by: Álvaro S. Roco, et al.
Published: (2021-04-01)

The Multifaceted p21 (Cip1/Waf1/<i>CDKN1A</i>) in Cell Differentiation, Migration and Cancer Therapy
by: Nina-Naomi Kreis, et al.
Published: (2019-08-01)

Restoring Fertility for Novel Interspecific Hybrids between <i>Kalanchoe garambiensis</i> and <i>K. nyikae</i> Using Colchicine Treatment
by: Yi Kuang, et al.
Published: (2021-01-01)

Subgenome Discrimination in <i>Brassica</i> and <i>Raphanus</i> Allopolyploids Using Microsatellites
by: Nicole Bon Campomayor, et al.
Published: (2021-09-01)

Molecular Genetics and Functional Analysis Implicate <i>CDKN2BAS1-CDKN2B </i>Involvement in POAG Pathogenesis
by: Sonika Rathi, et al.
Published: (2020-08-01)

The identity of <i>Erica vinacea</i> and notes on hybridization in Erica
by: E. G. H. Oliver
Published: (1986-07-01)

MicroRNA-148a Regulates the Proliferation and Differentiation of Ovine Preadipocytes by Targeting <i>PTEN</i>
by: Xiayang Jin, et al.
Published: (2021-03-01)

Loss of PSP94 expression is associated with early PSA recurrence and deteriorates outcome of <i>PTEN</i> deleted prostate cancers
by: Andreas M. Luebke, et al.
Published: (2019-06-01)

Genetic Diversity of Aquatic <i>Ranunculus</i> (<i>Batrachium</i>, Ranunculaceae) in One River Basin Caused by Hybridization
by: Jurgita Butkuvienė, et al.
Published: (2020-10-01)

Spatiotemporal Expression of Anticoagulation Factor <i>Antistasin</i> in Freshwater Leeches
by: Hee-Jin Kwak, et al.
Published: (2019-08-01)

Physical and Mechanical Properties of Fast Growing Polyploid Acacia Hybrids (<i>A. auriculiformis </i>× <i>A. mangium</i>) from Vietnam
by: Dang Duc Viet, et al.
Published: (2020-06-01)

Phylogenetics of <i>Taxus</i> Using the Internal Transcribed Spacers of Nuclear Ribosomal DNA and Plastid <i>trnL-F</i> Regions
by: Patricia Coughlan, et al.
Published: (2020-03-01)

Immune Response and Apoptosis-Related Pathways Induced by <i>Aeromonas schubertii</i> Infection of Hybrid Snakehead (<i>Channa maculata</i>♀ × <i>Channa argus</i>♂)
by: Chun Liu, et al.
Published: (2021-08-01)

Connection between Nutrient Content and Resistance to Selected Pests Analyzed in <i>Brassicaceae</i> Hybrids
by: Justyna Szwarc, et al.
Published: (2021-01-01)

Hybrids of <i>Cinchona</i> Alkaloids and Bile Acids as Antiparasitic Agents Against <i>Trypanosoma cruzi</i>
by: Daniel Musikant, et al.
Published: (2019-08-01)

Severe Concomitant <i>Physaloptera</i> sp., <i>Dirofilaria immitis</i>, <i>Toxocara cati</i>, <i>Dipylidium caninum</i>, <i>Ancylostoma</i> sp. and <i>Taenia taeniaeformis</i> Infection in a Cat
by: Jose Cesar Menk P. Lima, et al.
Published: (2021-01-01)

Fungal Pathogen Emergence: Investigations with an <i>Ustilago</i> <i>maydis</i> × <i>Sporisorium reilianum</i> Hybrid
by: Emilee R. M. Storfie, et al.
Published: (2021-08-01)

The Investigation of Associations between <i>TP53</i> rs1042522, <i>BBC3</i> rs2032809, <i>CCND1</i> rs9344, <i>EGFR</i> rs2227983 Polymorphisms and Breast Cancer Phenotype and Prognosis
by: Justina Bekampytė, et al.
Published: (2021-08-01)

Phenotypic and Genetic Variation of an Interspecific <i>Centaurium</i> Hybrid (<i>Gentianaceae</i>) and Its Parental Species
by: Tijana Banjanac, et al.
Published: (2019-07-01)

<i>Torreya jackii</i> (Taxaceae): A Special Species that is Genetically Admixed, Morphologically Distinct, and Geographically Sympatric with Parent Species
by: Yu-Jin Wang, et al.
Published: (2019-02-01)

Measurement of Chromosomal Arms and FISH Reveal Complex Genome Architecture and Standardized Karyotype of Model Fish, Genus <i>Carassius</i>
by: Martin Knytl, et al.
Published: (2021-09-01)

Application of A Genus-Specific LAMP Assay for Schistosome Species to Detect <i>Schistosoma haematobium</i> x <i>Schistosoma bovis</i> Hybrids
by: Beatriz Crego-Vicente, et al.
Published: (2021-03-01)

<i>Pseudomonas aeruginosa</i> Consumption of Airway Metabolites Promotes Lung Infection
by: Sebastián A. Riquelme, et al.
Published: (2021-07-01)

In Vitro Antifungal Activity and Toxicity of Dihydrocarvone-Hybrid Derivatives against <i>Monilinia fructicola</i>
by: Katy Díaz, et al.
Published: (2021-07-01)

Screening and Identification of Host Proteins Interacting with <i>Iris lactea</i> var. <i>chinensis</i> Metallothionein IlMT2a by Yeast Two-Hybrid Assay
by: Zhiquan Wang, et al.
Published: (2021-04-01)

Identification and Characterization of the <i>DMRT11E</i> Gene in the Oriental River Prawn <i>Macrobrachium nipponense</i>
by: Yabing Wang, et al.
Published: (2019-04-01)

Prevalence and Genetic Diversity of Staphylococcal Enterotoxin (-Like) Genes <i>sey</i>, <i>selw</i>, <i>selx</i>, <i>selz</i>, <i>sel26</i> and <i>sel27</i> in Community-Acquired Methicillin-Resistant <i>Staphylococcus aureus</i>
by: Meiji Soe Aung, et al.
Published: (2020-05-01)

Dissecting Taxonomic Variants within <i>Ulmus</i> spp. Complex in Natural Forests with the Aid of Microsatellite and Morphometric Markers
by: Sigitas Tamošaitis, et al.
Published: (2021-05-01)

The Kaumoebavirus LCC10 Genome Reveals a Unique Gene Strand Bias among “Extended <i>Asfarviridae</i>”
by: Khalil Geballa-Koukoulas, et al.
Published: (2021-01-01)

Pollen morphology of <i>Curroria</i>, <i>Mondia</i>, <i>Socotranthus</i> and <i>Stomatostemma</i> (Periplocaceae)
by: R. L. Verhoeven, et al.
Published: (1993-10-01)