Detection and Correlation of Single and Concomitant <i>TP53</i>, <i>PTEN,</i> and <i>CDKN2A</i> Alterations in Gliomas

Detection and Correlation of Single and Concomitant <i>TP53</i>, <i>PTEN,</i> and <i>CDKN2A</i> Alterations in Gliomas

Gliomas are the most frequent primary tumors of central nervous system and represent a heterogeneous group of tumors that originates from the glial cells. <i>TP53</i>, <i>PTEN</i>, and <i>CDKN2A</i> are important tumor suppressor genes that encode proteins involve...

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Bibliographic Details
Main Authors: Igor Andrade Pessôa, Carolina Koury Amorim, Wallax Augusto Silva Ferreira, Fernanda Sagica, José Reginaldo Brito, Moneeb Othman, Britta Meyer, Thomas Liehr, Edivaldo Herculano C. de Oliveira
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:International Journal of Molecular Sciences
Subjects:
glioma
<i>TP53</i>
<i>PTEN</i>
<i>CDKN2A</i>
co-alterations
single-strand conformational polymorphism
array-comparative genomic
hybridization and fluorescence in situ hybridization
Online Access:https://www.mdpi.com/1422-0067/20/11/2658

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https://www.mdpi.com/1422-0067/20/11/2658

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