An integrated framework for quantifying immune-tumour interactions in a 3D co-culture model

Al-Hity et al present a platform to study the tumour-immune interaction using a co-culture between cancer spheroids and activated immune cells. They assess the effects of cortisol application to the culture model as proof-of-concept, which demonstrates the potential for this platform as a screening...

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Bibliographic Details
Main Authors: Gheed Al-Hity, FengWei Yang, Eduard Campillo-Funollet, Andrew E. Greenstein, Hazel Hunt, Myrthe Mampay, Haya Intabli, Marta Falcinelli, Anotida Madzvamuse, Chandrasekhar Venkataraman, Melanie S. Flint
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02296-7
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Summary:Al-Hity et al present a platform to study the tumour-immune interaction using a co-culture between cancer spheroids and activated immune cells. They assess the effects of cortisol application to the culture model as proof-of-concept, which demonstrates the potential for this platform as a screening tool for immunotherapy design.
ISSN:2399-3642