Improvement of Water Solubility of Mercaptoundecahydrododecaborate (BSH)-Peptides by Conjugating with Ethylene Glycol Linker and Interaction with Cyclodextrin

We previously developed a conjugate consisting of <sup>10</sup>B cluster BSH and tri-arginine peptide (BSH-3R). This could potentially be used as a boron agent for boron neutron capture therapy; however, it possesses poor water solubility and thus needs to be improved for use as medicine...

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Bibliographic Details
Main Authors: Mizuki Kitamatsu, Ayaka Nakamura-Tachibana, Yoshimichi Ishikawa, Hiroyuki Michiue
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Processes
Subjects:
BSH
Online Access:https://www.mdpi.com/2227-9717/9/1/167