A Facile, One-Pot, Surfactant-Free Nanoprecipitation Method for the Preparation of Nanogels from Polyglycerol–Drug Conjugates that Can Be Freely Assembled for Combination Therapy Applications

A Facile, One-Pot, Surfactant-Free Nanoprecipitation Method for the Preparation of Nanogels from Polyglycerol–Drug Conjugates that Can Be Freely Assembled for Combination Therapy Applications

A well-established strategy to treat drug resistance is the use of multiple therapeutics. Polymer-based drug delivery systems (DDS) can facilitate a simultaneous delivery of two or more drugs. In this study, we developed and synthesized a dendritic polyglycerol (PG) nanogel (NG) system that allows f...

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Bibliographic Details
Main Authors: Laura I. Vossen, Stefanie Wedepohl, Marcelo Calderón
Format: Article
Language:English
Published: MDPI AG 2018-04-01
Series:Polymers
Subjects:
combination therapy
prodrug
polyglycerol
nanogel
doxorubicin
paclitaxel
Online Access:http://www.mdpi.com/2073-4360/10/4/398

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