Connexin43 Forms Supramolecular Complexes through Non-Overlapping Binding Sites for Drebrin, Tubulin, and ZO-1.

Gap junctions are membrane specialization domains identified in most tissue types where cells abut each other. The connexin channels found in these membrane domains are conduits for direct cell-to-cell transfer of ions and molecules. Connexin43 (Cx43) is the most ubiquitous connexin, with critical r...

Full description

Bibliographic Details
Main Authors: Cinzia Ambrosi, Cynthia Ren, Gaelle Spagnol, Gabriel Cavin, Angela Cone, Elena E Grintsevich, Gina E Sosinsky, Paul L Sorgen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4900556?pdf=render