Possible Prosthetic Valve Endocarditis by Pandoraea pnomenusa and Specific Virulence Mechanisms

• Main Authors: Bodendoerfer E, Personnic N, Mestres CA, Wilhelm MJ, Meyer L, Hasse B
• Format: Article
• Language: English
• Published: Dove Medical Press 2021-04-01
• Series: Infection and Drug Resistance
• Subjects: prosthetic valve endocarditis; central venous catheter; bacteremia; pandoraea pnomenusa; biofilm formation; antibiotic resistance
• Online Access: https://www.dovepress.com/possible-prosthetic-valve-endocarditis-by-pandoraea-pnomenusa-and-spec-peer-reviewed-article-IDR

Elias Bodendoerfer, 1 Nicolas Personnic, 1 Carlos A Mestres, 2 Markus J Wilhelm, 2 Lilly Meyer, 3 Barbara Hasse 3 1University of Zurich, Institute of Medical Microbiology, Zurich, Switzerland; 2University Hospital Zurich, Clinic for Cardiac Surgery, Zurich, Switzerland; 3University Hospital Zurich, Department of Infectious Diseases and Hospital Epidemiology, Zurich, SwitzerlandCorrespondence: Elias BodendoerferInstitute of Medical Microbiology, University of Zurich, Gloriastrasse 28/30, Zürich, CH-8006, SwitzerlandTel [phone]Email [e-mail]: Bacteremia by Pandoraea spp. has rarely been described before. We report the first case of a P. pnomenusa possible prosthetic valve endocarditis, according to the modified Duke criteria, in a 37-year old male injecting drug user suffering from recurrent endocarditis. Furthermore, we demonstrate biofilm formation by the P. pnomenusa isolates of this patient and investigate antibiotic resistance.Keywords: prosthetic valve endocarditis, central venous catheter, bacteremia, Pandoraea pnomenusa, biofilm formation, antibiotic resistance