Sphingomyelin exhibits greatly enhanced protection compared with egg yolk phosphatidylcholine against detergent bile salts1

Sphingomyelin exhibits greatly enhanced protection compared with egg yolk phosphatidylcholine against detergent bile salts1

Inclusion of phosphatidylcholine within bile salt micelles protects against bile salt-induced cytotoxicity. In addition to phosphatidylcholine, bile may contain significant amounts of sphingomyelin, particularly under cholestatic conditions. We compared protective effects of egg yolk phosphatidylcho...

Full description

Bibliographic Details
Main Authors: Antonio Moschetta, Gerard P. vanBerge-Henegouwen, Piero Portincasa, Giuseppe Palasciano, Albert K. Groen, Karel J. van Erpecum
Format: Article
Language:English
Published: Elsevier 2000-06-01
Series:Journal of Lipid Research
Subjects:
bile salts
CaCo-2 cells
erythrocytes
intermixed micellar-vesicular bile salt concentration
micelles
phosphatidylcholine
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520320332

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520320332

Similar Items