Modulating drug release from gastric-floating microcapsules through spray-coating layers.

Floating dosage forms with prolonged gastric residence time have garnered much interest in the field of oral delivery. However, studies had shown that slow and incomplete release of hydrophobic drugs during gastric residence period would reduce drug absorption and cause drug wastage. Herein, a spray...

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Bibliographic Details
Main Authors: Wei Li Lee, Jun Wei Melvin Tan, Chaoyang Nicholas Tan, Say Chye Joachim Loo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4254999?pdf=render