Improved DNA electrophoresis in conditions favoring polyborates and lewis acid complexation.

Spatial compression among the longer DNA fragments occurs during DNA electrophoresis in agarose and non-agarose gels when using certain ions in the conductive buffer, impairing the range of fragment sizes resolved well in a single gel. Substitutions using various polyhydroxyl anions supported the un...

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Bibliographic Details
Main Authors: Hari Singhal, Yunzhao R Ren, Scott E Kern
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2892876?pdf=render