Tamoxifen in Duchenne muscular dystrophy (TAMDMD): study protocol for a multicenter, randomized, placebo-controlled, double-blind phase 3 trial

Tamoxifen in Duchenne muscular dystrophy (TAMDMD): study protocol for a multicenter, randomized, placebo-controlled, double-blind phase 3 trial

Abstract Background Duchenne muscular dystrophy (DMD) is an inherited neuromuscular disorder of childhood with a devastating disease course. Several targeted gene therapies and molecular approaches have been or are currently being tested in clinical trials; however, a causative therapy is still not...

Full description

Bibliographic Details
Main Authors: Sara Nagy, Patricia Hafner, Simone Schmidt, Daniela Rubino-Nacht, Sabine Schädelin, Oliver Bieri, Dirk Fischer
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Trials
Subjects:
Duchenne muscular dystrophy
Tamoxifen
Motor function measure
6-min walk test
Quantitative muscle MRI
Randomized placebo-controlled trial
Online Access:http://link.springer.com/article/10.1186/s13063-019-3740-6

Similar Items

Similar Items