<it>Copynumber:</it> Efficient algorithms for single- and multi-track copy number segmentation

<it>Copynumber:</it> Efficient algorithms for single- and multi-track copy number segmentation

<p>Abstract</p> <p>Background</p> <p>Cancer progression is associated with genomic instability and an accumulation of gains and losses of DNA. The growing variety of tools for measuring genomic copy numbers, including various types of array-CGH, SNP arrays and high-thro...

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Bibliographic Details
Main Authors: Nilsen Gro, Liestøl Knut, Loo Peter Van, Moen Vollan Hans Kristian, Eide Marianne B, Rueda Oscar M, Chin Suet-Feung, Russell Roslin, Baumbusch Lars O, Caldas Carlos, Børresen-Dale Anne-Lise, Lingjærde Ole Christian
Format: Article
Language:English
Published: BMC 2012-11-01
Series:BMC Genomics
Subjects:
Copy number
aCGH
Segmentation
Allele-specific segmentation
Penalized regression
Least squares
Bioconductor
Online Access:http://www.biomedcentral.com/1471-2164/13/591

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