Mass-Forming Ischemic Colitis: A Potential Mimicker of Malignancy
Ischemic colitis (IC) results from reduced colonic vascular perfusion, accounting for 50-60% of all gastrointestinal ischemic episodes. IC leads to mucosal damage with clinical symptom severity developing based on the duration and extent of colonic injury. In rare cases IC may form a mass-like lesio...
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2019-01-01
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Series: | Case Reports in Pathology |
Online Access: | http://dx.doi.org/10.1155/2019/8927872 |
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doaj-c9051391176f488883a2cbe2c66e318d2020-11-24T21:46:30ZengHindawi LimitedCase Reports in Pathology2090-67812090-679X2019-01-01201910.1155/2019/89278728927872Mass-Forming Ischemic Colitis: A Potential Mimicker of MalignancyAlexandra M. Danakas0Bushra G. Fazili1Aaron R. Huber2Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, 601 Elmwood Ave, Box 626, Rochester, NY 14642, USADepartment of Medicine Division of Gastroenterology/Hepatology, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14642, USADepartment of Pathology and Laboratory Medicine, University of Rochester Medical Center, 601 Elmwood Ave, Box 626, Rochester, NY 14642, USAIschemic colitis (IC) results from reduced colonic vascular perfusion, accounting for 50-60% of all gastrointestinal ischemic episodes. IC leads to mucosal damage with clinical symptom severity developing based on the duration and extent of colonic injury. In rare cases IC may form a mass-like lesion mimicking malignancy. Here we present the case of a 55-year-old female with hematochezia and diarrhea, who on workup was found to have a mass-like lesion at the ileocecal valve. Multiple biopsies demonstrated ischemic change and mucosal injury without evidence of dysplasia or carcinoma. Two months later on follow-up imaging, after supportive treatment the lesion was completely resolved. It is critical for gastroenterologists and pathologists to be aware of this variant of IC to avoid unnecessary surgical procedures and treatment of patients.http://dx.doi.org/10.1155/2019/8927872 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Alexandra M. Danakas Bushra G. Fazili Aaron R. Huber |
spellingShingle |
Alexandra M. Danakas Bushra G. Fazili Aaron R. Huber Mass-Forming Ischemic Colitis: A Potential Mimicker of Malignancy Case Reports in Pathology |
author_facet |
Alexandra M. Danakas Bushra G. Fazili Aaron R. Huber |
author_sort |
Alexandra M. Danakas |
title |
Mass-Forming Ischemic Colitis: A Potential Mimicker of Malignancy |
title_short |
Mass-Forming Ischemic Colitis: A Potential Mimicker of Malignancy |
title_full |
Mass-Forming Ischemic Colitis: A Potential Mimicker of Malignancy |
title_fullStr |
Mass-Forming Ischemic Colitis: A Potential Mimicker of Malignancy |
title_full_unstemmed |
Mass-Forming Ischemic Colitis: A Potential Mimicker of Malignancy |
title_sort |
mass-forming ischemic colitis: a potential mimicker of malignancy |
publisher |
Hindawi Limited |
series |
Case Reports in Pathology |
issn |
2090-6781 2090-679X |
publishDate |
2019-01-01 |
description |
Ischemic colitis (IC) results from reduced colonic vascular perfusion, accounting for 50-60% of all gastrointestinal ischemic episodes. IC leads to mucosal damage with clinical symptom severity developing based on the duration and extent of colonic injury. In rare cases IC may form a mass-like lesion mimicking malignancy. Here we present the case of a 55-year-old female with hematochezia and diarrhea, who on workup was found to have a mass-like lesion at the ileocecal valve. Multiple biopsies demonstrated ischemic change and mucosal injury without evidence of dysplasia or carcinoma. Two months later on follow-up imaging, after supportive treatment the lesion was completely resolved. It is critical for gastroenterologists and pathologists to be aware of this variant of IC to avoid unnecessary surgical procedures and treatment of patients. |
url |
http://dx.doi.org/10.1155/2019/8927872 |
work_keys_str_mv |
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1725901742863810560 |