Mass-Forming Ischemic Colitis: A Potential Mimicker of Malignancy

Ischemic colitis (IC) results from reduced colonic vascular perfusion, accounting for 50-60% of all gastrointestinal ischemic episodes. IC leads to mucosal damage with clinical symptom severity developing based on the duration and extent of colonic injury. In rare cases IC may form a mass-like lesio...

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Main Authors: Alexandra M. Danakas, Bushra G. Fazili, Aaron R. Huber
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Case Reports in Pathology
Online Access:http://dx.doi.org/10.1155/2019/8927872
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spelling doaj-c9051391176f488883a2cbe2c66e318d2020-11-24T21:46:30ZengHindawi LimitedCase Reports in Pathology2090-67812090-679X2019-01-01201910.1155/2019/89278728927872Mass-Forming Ischemic Colitis: A Potential Mimicker of MalignancyAlexandra M. Danakas0Bushra G. Fazili1Aaron R. Huber2Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, 601 Elmwood Ave, Box 626, Rochester, NY 14642, USADepartment of Medicine Division of Gastroenterology/Hepatology, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14642, USADepartment of Pathology and Laboratory Medicine, University of Rochester Medical Center, 601 Elmwood Ave, Box 626, Rochester, NY 14642, USAIschemic colitis (IC) results from reduced colonic vascular perfusion, accounting for 50-60% of all gastrointestinal ischemic episodes. IC leads to mucosal damage with clinical symptom severity developing based on the duration and extent of colonic injury. In rare cases IC may form a mass-like lesion mimicking malignancy. Here we present the case of a 55-year-old female with hematochezia and diarrhea, who on workup was found to have a mass-like lesion at the ileocecal valve. Multiple biopsies demonstrated ischemic change and mucosal injury without evidence of dysplasia or carcinoma. Two months later on follow-up imaging, after supportive treatment the lesion was completely resolved. It is critical for gastroenterologists and pathologists to be aware of this variant of IC to avoid unnecessary surgical procedures and treatment of patients.http://dx.doi.org/10.1155/2019/8927872
collection DOAJ
language English
format Article
sources DOAJ
author Alexandra M. Danakas
Bushra G. Fazili
Aaron R. Huber
spellingShingle Alexandra M. Danakas
Bushra G. Fazili
Aaron R. Huber
Mass-Forming Ischemic Colitis: A Potential Mimicker of Malignancy
Case Reports in Pathology
author_facet Alexandra M. Danakas
Bushra G. Fazili
Aaron R. Huber
author_sort Alexandra M. Danakas
title Mass-Forming Ischemic Colitis: A Potential Mimicker of Malignancy
title_short Mass-Forming Ischemic Colitis: A Potential Mimicker of Malignancy
title_full Mass-Forming Ischemic Colitis: A Potential Mimicker of Malignancy
title_fullStr Mass-Forming Ischemic Colitis: A Potential Mimicker of Malignancy
title_full_unstemmed Mass-Forming Ischemic Colitis: A Potential Mimicker of Malignancy
title_sort mass-forming ischemic colitis: a potential mimicker of malignancy
publisher Hindawi Limited
series Case Reports in Pathology
issn 2090-6781
2090-679X
publishDate 2019-01-01
description Ischemic colitis (IC) results from reduced colonic vascular perfusion, accounting for 50-60% of all gastrointestinal ischemic episodes. IC leads to mucosal damage with clinical symptom severity developing based on the duration and extent of colonic injury. In rare cases IC may form a mass-like lesion mimicking malignancy. Here we present the case of a 55-year-old female with hematochezia and diarrhea, who on workup was found to have a mass-like lesion at the ileocecal valve. Multiple biopsies demonstrated ischemic change and mucosal injury without evidence of dysplasia or carcinoma. Two months later on follow-up imaging, after supportive treatment the lesion was completely resolved. It is critical for gastroenterologists and pathologists to be aware of this variant of IC to avoid unnecessary surgical procedures and treatment of patients.
url http://dx.doi.org/10.1155/2019/8927872
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AT bushragfazili massformingischemiccolitisapotentialmimickerofmalignancy
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