The volatile anesthetic sevoflurane attenuates ventilator-induced lung injury through inhibition of ERK1/2 and Akt signal transduction

The volatile anesthetic sevoflurane attenuates ventilator-induced lung injury through inhibition of ERK1/2 and Akt signal transduction

BackgroundVentilator-induced lung injury (VILI) sustained during mechanical ventilator support is still a cause of a high rate of morbidity and mortality in intensive care units and in operating rooms. VILI is characterized by pulmonary inflammation that appears to be mediated by proinflammatory cyt...

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Bibliographic Details
Main Authors: Sang-Hun Kim, Mei Li, Tae-Hee Pyeon, Keum-Young So, Sang-Hyun Kwak
Format: Article
Language:English
Published: Korean Society of Anesthesiologists 2015-02-01
Series:Korean Journal of Anesthesiology
Subjects:
akt
erk1/2
sevoflurane
ventilator-induced lung injury
Online Access:http://ekja.org/upload/pdf/kjae-68-62.pdf

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