Impairment of rat fetal beta-cell development by maternal exposure to dexamethasone during different time-windows.

AIM:Glucocorticoids (GCs) take part in the direct control of cell lineage during the late phase of pancreas development when endocrine and exocrine cell differentiation occurs. However, other tissues such as the vasculature exert a critical role before that phase. This study aims to investigate the...

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Bibliographic Details
Main Authors: Olivier Dumortier, Nicolas Theys, Marie-Thérèse Ahn, Claude Remacle, Brigitte Reusens
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3184993?pdf=render