Architecture of the Saccharomyces cerevisiae NuA4/TIP60 complex

The NuA4 histone acetyltransferase complex is important for gene regulation, DNA repair processes and cell cycle progression. Here the authors give molecular insights into the NuA4 complex by presenting the cryo-EM structures of the NuA4 TEEAA (Tra1, Eaf1, Eaf5, actin, and Arp4) and TEEAA-piccolo Nu...

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Bibliographic Details
Main Authors: Xuejuan Wang, Salar Ahmad, Zhihui Zhang, Jacques Côté, Gang Cai
Format: Article
Language:English
Published: Nature Publishing Group 2018-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-03504-5