A Drosophila model for mito-nuclear diseases generated by an incompatible interaction between tRNA and tRNA synthetase
Communication between the mitochondrial and nuclear genomes is vital for cellular function. The assembly of mitochondrial enzyme complexes, which produce the majority of cellular energy, requires the coordinated expression and translation of both mitochondrially and nuclear-encoded proteins. The joi...
Main Authors: | Marissa A. Holmbeck, Julia R. Donner, Eugenia Villa-Cuesta, David M. Rand |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2015-08-01
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Series: | Disease Models & Mechanisms |
Subjects: | |
Online Access: | http://dmm.biologists.org/content/8/8/843 |
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