PDR Transporter ABC1 Is Involved in the Innate Azole Resistance of the Human Fungal Pathogen Fusarium keratoplasticum

PDR Transporter ABC1 Is Involved in the Innate Azole Resistance of the Human Fungal Pathogen Fusarium keratoplasticum

Fusarium keratoplasticum is arguably the most common Fusarium solani species complex (FSSC) species associated with human infections. Invasive fusariosis is a life-threatening fungal infection that is difficult to treat with conventional azole antifungals. Azole drug resistance is often caused by th...

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Bibliographic Details
Main Authors: Jasper Elvin James, Erwin Lamping, Jacinta Santhanam, Richard David Cannon
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Microbiology
Subjects:
azole
PDR transporter
drug efflux
FSSC
Fusarium keratoplasticum
fusariosis
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.673206/full

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