Recombineering strategies for developing next generation BAC transgenic tools for optogenetics and beyond

Recombineering strategies for developing next generation BAC transgenic tools for optogenetics and beyond

The development and application of diverse BAC transgenic rodent lines has enabled rapid progress for precise molecular targeting of genetically-defined cell types in the mammalian central nervous system. These transgenic tools have played a central role in the optogenetic revolution in neuroscienc...

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Bibliographic Details
Main Authors: Jonathan T Ting, Guoping eFeng
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-04-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Dopamine
Gene Dosage
Homologous Recombination
Striatum
optogenetics
gensat
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00111/full

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