SUMO-SIM interactions regulate the activity of RGSZ2 proteins.

The RGSZ2 gene, a regulator of G protein signaling, has been implicated in cognition, Alzheimer's disease, panic disorder, schizophrenia and several human cancers. This 210 amino acid protein is a GTPase accelerating protein (GAP) on Gαi/o/z subunits, binds to the N terminal of neural nitric ox...

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Bibliographic Details
Main Authors: Javier Garzón, María Rodríguez-Muñoz, Ana Vicente-Sánchez, María Ángeles García-López, Ricardo Martínez-Murillo, Thierry Fischer, Pilar Sánchez-Blázquez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3232247?pdf=render