PA from an H5N1 highly pathogenic avian influenza virus activates viral transcription and replication and induces apoptosis and interferon expression at an early stage of infection

PA from an H5N1 highly pathogenic avian influenza virus activates viral transcription and replication and induces apoptosis and interferon expression at an early stage of infection

<p>Abstract</p> <p>Background</p> <p>Although gene exchange is not likely to occur freely, reassortment between the H5N1 highly pathogenic avian influenza virus (HPAIV) and currently circulating human viruses is a serious concern. The PA polymerase subunit of H5N1 HPAIV...

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Bibliographic Details
Main Authors: Wang Qiang, Zhang Shijian, Jiang Hongbing, Wang Jinlan, Weng Leiyun, Mao Yingying, Sekiguchi Satoshi, Yasui Fumihiko, Kohara Michinori, Buchy Philippe, Deubel Vincent, Xu Ke, Sun Bing, Toyoda Tetsuya
Format: Article
Language:English
Published: BMC 2012-06-01
Series:Virology Journal
Subjects:
Influenza virus
PA
Transcription
Replication
Apoptosis
Interferon
Online Access:http://www.virologyj.com/content/9/1/106

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