Sugammadex is associated with better respiratory recovery than neostigmine following reversal of anaesthesia-associated neuromuscular blockade in the morbidly obese patients following elective laparoscopic surgery

• Main Authors: M. Johnson, O.A. Khan, E.R. McGlone, A.A. Roman, J.S. Qureshi, A. Kayal
• Format: Article
• Language: English
• Published: KeAi Communications Co., Ltd. 2018-09-01
• Series: Laparoscopic, Endoscopic and Robotic Surgery
• Online Access: http://www.sciencedirect.com/science/article/pii/S2468900917300130

Complete and reliable neuromuscular reversal is important to successful anaesthetic recovery in the morbidly obese patient undergoing laparoscopic surgery. Our goal was to determine whether sugammadex, a selective reversal agent is associated with better respiratory recovery than neostigmine following the reversal of anaesthesia-associated neuromuscular blockade by rocuronium in the morbidly obese. Peak Expiratory Flow Rate a surrogate marker for respiratory function, was the primary outcome measured and secondary outcome measures included post-operative nausea and vomiting, pain and head lifting. We found that patients reversed with sugammadex had a significantly higher post-operative PEFR as compared to those reversed with neostigmine and glycopyrrolate group. Keywords: Sugammadex, Laparoscopic surgery, Neuromuscular blockade, Morbidly obese