Summary: | Complete and reliable neuromuscular reversal is important to successful anaesthetic recovery in the morbidly obese patient undergoing laparoscopic surgery. Our goal was to determine whether sugammadex, a selective reversal agent is associated with better respiratory recovery than neostigmine following the reversal of anaesthesia-associated neuromuscular blockade by rocuronium in the morbidly obese. Peak Expiratory Flow Rate a surrogate marker for respiratory function, was the primary outcome measured and secondary outcome measures included post-operative nausea and vomiting, pain and head lifting. We found that patients reversed with sugammadex had a significantly higher post-operative PEFR as compared to those reversed with neostigmine and glycopyrrolate group. Keywords: Sugammadex, Laparoscopic surgery, Neuromuscular blockade, Morbidly obese
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